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A meta-analysis of randomized controlled trials (RCTs) including patients with HF found no improvement in hospitalization rates or echocardiographic parameters such as LVEF or LV end-systolic or diastolic volume
Endocrinol Metab (Seoul) 2019;34(3):247262

Some of these effects often require a combination therapy in advanced T2DM, leading thus to increased healthcare costs and associated high risks of drug interaction [10]

Studies show that 12 weeks of treatment with high-dose green tea extract results in weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels