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In the current review, we discussed the dysregulation of IGF-1/GLP-1 signaling in neurodegenerative manifestations of ALS like a genetic anomaly, oligodendrocyte degradation, demyelination, glial overactivation, immune deregulation, and neuroexcitation

In an investigative report in partnership with KFF Health News, NBC News Anne Thompson reports on the growing cases of overdoses involving GLP-1 weight loss drugs.

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Learn how this dual incretin receptor agonist was developed, its FDA-approved uses for diabetes and weight management, and essential clinical considerations for safe prescribing.