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Recently, multiple case reports and studies indicating safety risks for these medications and their use in patients planning to undergo general anesthesia have been published, as retained gastric contents can lead to intraoperative aspiration

Most recently on 8 November 2023, the US Food and Drug Administration approved through an expedited process the use of tirzepatide (Zepbound®) for chronic weight management in adults with obesity, reflecting the urgent need to address gaps in obesity treatment

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