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Adverse events leading people to stop pemvidutide occurred in 2 people (12.5%) taking 1.2 mg, 1 (6.7%) taking 1.3 mg, and none taking 2.4 mg

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This specific localization within the GCL is of profound clinical relevance, as retinal ganglion cells are the primary neurons that degenerate in glaucoma and are also critically affected during the early neurodegenerative stages of diabetic retinopathy [38, 39]