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Gut (2003) 52:94752
Sleep deprivation and chronic stress boost cortisol levels that promote fat storage and increase appetite through pathways that semaglutide can't fully counteract

Freeland KR, Wilson C, Wolever TM

Rapid weight changes can affect spinal loading patterns and muscular support, potentially contributing to transient back discomfort as the body adapts

4 Following the observation of weight reductions in T2D, 4 GLP1RAs were studied in patients with overweight or obesity, 5 , 6 and a single agent (liraglutide 3 mg) is currently approved for weight management
