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Nausea, GI discomfort, constipation, fatigue, and other symptoms can occur, especially when starting treatment or adjusting the dose

Due to tissue-specific posttranslational processing, GLP-1 is predominantly made in the gut and brain but can also be made in the pancreatic -cells in response to nutrients and under times of stress

What will happen to customers' prescriptions

The overall goal will be to reproduce the physiological consequences of a gastric bypass procedure solely by means of gut hormone based therapy, thereby effectively creating a 'medical bypass.' Footnotes Akila De Silva has no competing interests to declare

The Congressional Budget Office estimates that 29 million Medicare beneficiaries would then qualify for GLP-1 drug coverage, although 16 million already have access for conditions such as diabetes or cardiovascular disease