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Adding to this, people feel full for longer periods, and again, this helps regulate appetite and eating patterns

However, recent studies have shown that psilocybin administration leads to a significant increase in AMPA current amplitude, while NMDA current amplitude remained unchanged, indicating that psilocybin-induced synaptic enhancement may be regulated by postsynaptic AMPAR activity (Hesselgrave et al., 2021)

Wound Repair Regen 2020;28:493505

Some protocols skip this dose and move directly from 5 mg to 10 mg, particularly for individuals tolerating the 5 mg dose well with minimal side effects

doi: 10.1177/1479164115605000 41 TateMRobinsonEGreenBDMcDermottBJGrieveDJ