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We don't have good data on: *What outcomes look like at various sub-therapeutic doses *Which patients might benefit from lower, more frequent dosing versus higher, less frequent *How hormonal changes (hello, perimenopause) affect optimal dosing *Long-term effects of maintenance microdosing after weight loss goals are met The doctor quoted in the article is right that standard doses exist because they've been proven effective

She critiques a marketplace that often treats these powerful medications as consumer products rather than chronic disease therapies, noting the risks of obtaining prescriptions through brief online questionnaires without ongoing medical oversight
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Most people regain weight within months of stopping Zepbound because the medication addresses appetite and metabolism temporarily, not permanently
Experts have some real concerns.
