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And so, what they do is they reduce appetite, and they improve blood sugar control, and they promote weight loss

doi: 10.3390/nu13124321
Semaglutide targets GLP-1 receptors, while tirzepatide is a dual GIP/GLP-1 receptor agonist

Moreover, inhibition of PFKFB3 by 3PO has been shown to exert anti-inflammatory and antifibrotic effects on experimental lung fibrosis in mice [12]

It is a triple agonist, adding glucagon receptor activation to the mix, and that third receptor changes everything from thermogenesis to liver fat metabolism to the total percentage of body weight people lose in controlled studies
