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Mechanism of Action Serotonin and Norepinephrine Reuptake Inhibition Venlafaxine increases serotonin and norepinephrine levels in the brain by preventing their reabsorption

15 A significant nuance of this system is the NCE-1 provision, which allows a generic manufacturer to file an ANDA with a Paragraph IV certification four years after the NCEs approval, provided they challenge at least one of the patents listed in the FDAs Orange Book

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But researchers discovered a powerful side effect during clinical trials: it also helps patients lose weight significantly