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28 The efficacy of semaglutide in obesity treatment has been demonstrated in the STEP program

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Medium dose (4mg weekly) This is where the glucagon component becomes active and side effects become more noticeable

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A comprehensive medical evaluationincluding metabolic bloodwork, thyroid function, and kidney disease screeningmust precede treatment initiation

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~14% with semaglutide over 72 weeks

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Mounjaro is even more distinct because tirzepatide acts on both GIP and GLP-1 receptors

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