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PMID: 34497589
For type 2 diabetes (NICE NG28), GLP-1 receptor agonists are generally considered after metformin-based therapy has proven insufficient, and can be initiated in primary care according to local formularies and prescribing arrangements
The interaction of GLP-1 with its receptor leads to an increase in intracellular cAMP levels and activation of numerous cellular processes that vary depending on the organ or system involved [5]
