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Description
Cohort entry was defined as the date of the first-ever prescription for one of the drugs of interest (GLP-1RAs, SGLT2 inhibitors, metformin or other second- or third-line glucose-lowering drugs) during the study period, and their respective first exposure was defined as the index event

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Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors

Final Thoughts Retatrutide has emerged as one of the most exciting developments in the peptide industry

Several peptides with strong physiological phenotypes were identified before their receptors were cloned or fully characterized, limiting structureactivity relationship studies and medicinal chemistry optimization
