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Description
Effects of steatotic liver disease and cardiometabolic risk factors in MASLD on adverse pregnancy outcomes
A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endothelial dysfunction
Other Diabetes Medications: Metformin, SGLT2 inhibitors, and DPP-4 inhibitors may be suitable alternatives
Johns Hopkins MD
To validate the observed closed conformation and to study their effects on receptor activation, we engineered disulfide bonds on the wild-type GLP-1R to lock the interactions between the ECD and ECL1/3
