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However, for those that do not wish to partake in surgery, current data shows: Wegovy: Most effective GLP-1 for weight loss (up to 15% of body weight)
2018 Jul;14(7):390-403
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This resistance is sensed as starvation, so multiple mechanisms are activated to increase fat stores rather than burn excess fat stores
These facts, together with increasing comorbidities in patients with IBD, imply that urgent, more complex, novel therapeutic strategies in the treatment are needed
