what was glp 1 originally used for History of glucagon-like peptide-1 receptor agonists GLP-1 receptor agonists are increasingly

In the SURMOUNT-1 trial, tirzepatide produced dose-dependent weight reductions, with average losses approaching or exceeding ~20% at higher doses in adults with obesity who did not have diabetes, numbers that markedly exceed historical pharmacotherapy benchmarks

Also, disappointing to see not a RD on the paper but its littered with nutrition advice

The effects on babies are not fully known, so providers often advise postponing therapy until it is safe

You may be able to minimize skin stretching, and these effects, by maintaining good nutrition and hydration, and undergoing gradual rather than rapid weight loss under the care of a physician

(33) The limited data underscore the need for further research to clarify appropriate dosing, treatment duration, and the potential effects on growth and development in pediatric populations