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When Medications Arent an Option Some patients cannot use GLP-1s because of: Side effects (severe nausea, vomiting, or GI intolerance) Cost or insurance barriers Contraindications or personal preference For them, surgery may still offer the most realistic long-term benefit

Circulation 146(24):18821894 [DOI] [PubMed] [Google Scholar] Mary P, Curtis R (2010) Weighing risks and benefits of liraglutide the FDAs review of a new antidiabetic therapy

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The patients showed an adjusted mean change (AM) in HbA1c levels, from baseline to endpoint, of -0.8 0.1% ( P = 0.001 vs