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Clin Drug Investig 2019;39:805-819

Personalized Nutrition With Semaglutide: Your Genetic Blueprint Some patients naturally respond better to semaglutide than others based on their genetic predispositions to appetite control and metabolic pathways

Weight-loss use is not appropriate during pregnancy, and both are not recommended in severe gastroparesis

And I think that may be the angst that we're all having here