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Johns Wort Amphetamines Drugs that affect blood clotting such as: Medications that affect the heart rhythm (QT prolongation), including: Amiodarone Pimozide Procainamide Quinidine Sotalol Drugs that cause drowsiness: Alcohol Marijuana Antihistamines Medications for sleep or anxiety Muscle relaxants What does your healthcare provider need to know before you start Lexapro

While direct comparison studies haven't been completed, preliminary evidence suggests potentially larger effects than existing FDA-approved medications, particularly at the lower doses tested for alcohol use disorder

Up to 10% of clinical trial participants experienced these reactions

The work identifies SLC6A20 as a promising treatment target for restoring NMDAR function and offers a possible framework for addressing a wider group of neurodevelopmental and neuropsychiatric disorders connected to NMDAR hypofunction

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