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Without insurance, Mounjaro can cost $499 for a 1-month prescription of single-dose pens (all strengths) through the LillyDirect Mounjaro Self Pay Journey Program

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The specific amount of weight you might lose from Zepbound is uncertain, but significant weight loss ranging from 35.5 lb (16.1 kg) to 52.0 lb (23.6 kg) was observed in the 72-week SURMOUNT-1 clinical trial, which compared different Zepbound (tirzepatide) doses to a placebo (inactive treatment)

drugmaker expects a roughly 25% increase in revenue this year while Novos sales are expected to fall between 5% and 13% in 2026, in the clearest sign of the rivals divergent paths in a market increasingly driven by consumer demand rather than insurance coverage