5th gen glp 1 agonist Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia Frontiers | Unlocking the potential

The median follow-up duration was 1 year (IQR: 0.52 years), with key findings including a median weight loss of 11.7 kg and a median BMI at the most recent follow-up of 31.2 kg/m 2 , reflecting a median reduction of 3.7 kg/m 2

Furthermore, cell bodies that are immunoreactive to GLP-1 antisera are detected in the NTS, and GLP-1 immunoreactive nerve fibers are widely distributed throughout the brain with highest density in the hypothalamus, thalamus and septal regions whereas the lowest density is in the cortex and hindbrain [86,698]

Acknowledgments I thank Lily Lu, MD, PhD for her critical comments and David Liu and Erika Liu for their assistance with editing

1):S90-S102

While findings so far are promising, understanding the nuances of the evidence is essential when talking with patients