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The phase 2a liver-specific trial showed: 1 mg dose: 42.9% reduction in liver fat 4 mg dose: 57.0% reduction in liver fat 8 mg dose: 81.4% reduction in liver fat 12 mg dose: 82.4% reduction in liver fat An 82% reduction in liver fat is extraordinary

* This statement has not been evaluated by the Food & Drug Administration

Food and Drug Administration (FDA) has added a new warning to the weight-loss medication Wegovy, highlighting potential gastrointestinal reactions and stressing that individuals with severe gastroparesis should not take Wegovy

Concurrently, clinicians have observed increased conception rates among individuals using GLP-1 RAs, prompting investigation into whether these effects stem from improved metabolic health or direct pharmacologic influences on reproductive physiology

These data indicate that d-allulose ameliorates basal hyperglycemia and impaired glucose tolerance (IGT) in HFD-fed mice via GLP-1R signaling