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In humans, however, randomized trials with fertility endpoints are lacking

Fact : GLP-1 weight-loss drugs are typically prescribed to people with a BMI of 30 or higher

The development of novel dual- or triple-receptor agonists that bind to the receptors not only for GLP-1 but also to the receptors for glucose-dependent insulinotropic polypeptide (GIP) and/or glucagon is intended to address different metabolic pathways for carbohydrate, lipid, and protein metabolism simultaneously

doi: 10.1016/j.biopha.2018.08.088 142 SheikhA
