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In some patients, it shows a weight-reducing effect of nearly 30 percent, a level expected when conducting obesity metabolic surgery. Park added all these show obese people can reduce weight to a certain extent without surgeries

A budget impact analysis from a health system perspective indicated the use of tirzepatide could result in an additional financial burden ranging from $80 million to $490 million over 5 years on the National Health Insurance System (NHIS) (Zhang and McAdam Marx 2023)

When switched to placebo there was invariably weight regain, implying that the loss of inhibition of hyperphagia drove this process

After losing a significant amount of weight, your body may require fewer calories to maintain its current state

Long-term cost commitment - While $114-$263/month is affordable compared to brand-name medications, it's still a recurring cost
