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Importantly, multiple large randomized clinical trials have since demonstrated the remarkable effect of this class of drugs in preventing adverse renal outcomes in patients with diabetic nephropathy but also a diverse range of other chronic kidney diseases 5,6
Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]
Exenatide for weight-loss maintenance in adolescents with severe obesity: A randomized, placebo-controlled trial
More than half of those on the highest dose lost at least 10 percent of their weight
Regular check-ins ensure that your progress is tracked, questions are answered, and your treatment plan is adjusted for the best possible results
