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Description
This receptor transports A in opposite direction to LRP-1 mediating the re-entry of circulating A into the brain and thereby promoting neurovascular inflammation ( in vitro study showed that A can increase the expression of RAGE, thus promoting a positive feedback loop (Wan et al., 2015)
& Esplugues, J
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The primary endpoint was the change in the diacron-reactive oxygen metabolites test, an oxidative stress marker
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