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They may help prevent deficiencies that impair metabolic function, essentially removing obstacles rather than actively enhancing pathways

However, if you experience sudden or severe pain, blood in your stool, persistent vomiting, or yellowing of the skin or eyes, contact your healthcare provider immediately

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Bedtime NPH/Glargine Continue daytime oral hypoglycaemic agents: especially sulphonylureas (The BIDS regimen) Advantage: Once daily dosing Easy dose titration Disadvantage: May need premeal bolus NPH NPH Glargine Glargine Bedtime Long- acting Advantages Single Daily dosing Disadvantages Suitable for only 5kg

66 Compared to GIP (142), GIP (139) has a higher ability to modulate calcium and thus a stronger insulinotropic effect