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Clinical Evidence: Retatrutide's Impressive Results In a recent phase 2 trial for obesity, retatrutide demonstrated remarkable efficacy: Up to 24.2% weight loss at 48 weeks with the highest dose, surpassing the weight loss seen with both semaglutide(15-17%)and tirzepatide (22.5%) at their respective highest doses

Acarbose is therefore a valuable option for the management of type 2 diabetes and, as the only oral antidiabetes agent approved for the treatment of prediabetes, can help to improve clinical management across the dysglycaemic disease continuum.

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however, causal data are limited, and further longitudinal studies are required.Taken together, obesity represents a major modifiable determinant of pancreatic health, with implications spanning steatosis, inflammatory diseases, and malignancy