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Additional studies demonstrated that SREBP-1c -/- mice had impaired induction of hepatic genes coding for fatty acid biosynthesis (e.g., acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase) compared to wild type mice [17]
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The PK data on ACEI and GLP1 agonist co-treatment showed different effects by different GLP1RAs (Table 3)
