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Hydroxyurea, a cornerstone of sickle cell treatment, is considered a teratogen, so it comes off the table

doi: 10.1210/endo.139.10.6228

The beneficial effects observed in those patients with early onset, low atherosclerotic burden include an improvement in plaque stability score in the brachiocephalic artery, attenuation of lipid deposits in the aorta, and reduction of weight gain

The researchers of that study called for urgent clarification of drug- and patient-related risk factors, an understanding that has become more important as GLP-1 receptor agonist use continues to rise across the United States, especially for weight management

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