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Leptin alters hippocampal synaptic plasticity, improves learning and memory, and protects against several neurodegenerative diseases, including AD and Parkinsons disease (PD) [280]

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Ozempic is approved for type 2 diabetes (0.25 mg to 2 mg), while Wegovy is approved for chronic weight management (up to 2.4 mg) and to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either overweight or obesity Exenatide extended-release (Bydureon BCise) : Once-weekly injection using microsphere technology Liraglutide (Victoza, Saxenda) : Once-daily injection
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In response to the modest and mixed results gleaned from this study, Guo said her team of researchers plans to continue investigating the potential antidepressant effects of GLP-1RAs