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For eligible children with obesity, it is advisable to initiate treatment as early as possible

Note: These products alone are not intended to diagnose, treat, cure, or prevent any disease

Abbreviations ADA: American Diabetes Association CV: Cardiovascular CVOTs: Cardiovascular outcome trials GLP-1RA: Glucagon-like peptide-1 receptor agonists HR: Hazard ratios MACE: Major cardiovascular events SGLT-2i: Sodiumglucose transporter-2 inhibitors T2DM: Type 2 diabetes mellitus References Giugliano D, Maiorino MI, Longo M, Bellastella G, Chiodini P, Esposito K

18 DPP-4 inhibitor therapy is not associated with weight loss, which is attributed to a negligible effect of these agents on gastric emptying

doi:10.1007/s40262-020-00976-x 141