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In this review, we summarize several key signaling pathways closely involved in the pathogenesis of PCOS: the PI3K/Akt, TLR4/NF-B, Nrf2/HO-1, AMPK, MAPK, JAK/STAT, Wnt/-catenin, Notch, Hippo/YAP, TGF-/Smads, and hedgehog pathways

GLP-1 receptor agonists (GLP-1 RAs) have transformed obesity and Type 2 diabetes mellitus (T2DM) management, offering benefits in glucose regulation, weight loss, and cardiometabolic health (6)

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