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Many women benefit from HRT, and some can stay on therapy long-term under monitoring

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18 In these patients, pre-existing risk factors for biliary disease, such as insulin resistance (IR), dyslipidemia, and metabolic alterations, predispose them to abnormal bile composition and an increased risk of gallstone formation

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Haase CL, Serratore Achenbach MG, Lucrezi G, et al

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