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More clients are presenting with: Lower back pain, Hip and knee discomfort, Neck and shoulder issues, Or simply a feeling of being weaker and less stable

These findings reinforce an increasingly accepted concept: obesity behaves much like hypertension or diabetesa chronic, relapsing disease requiring long-term management rather than a short therapeutic course

Limiting the analysis to those with a BMI of 35 or higher brought dropout rates down to 8.8% for the low dose and 12.1% for the high dose, compared with 4.8% for the placebo closer to the rates seen in Zepbound trials, but still higher

One study showed that metformin significantly decreased thyroid nodule size by 30%50% in patients with insulin resistance [103]

But its not the same as physical or psychological addiction