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It also highlights when caution, monitoring, or dose adjustments may be helpful

Participants were also grouped based on the length of time they reported they had weight issues or obesity: 10 years or less Between 10 and 20 years More than 20 years The scientists evaluated the percentage of change in body weight and waist circumference when participants achieved weight loss targets of 5%, 10%, 15%, 20%, and 25% of total body weight

For example, a relatively high level of GLP-1R-immunoreactivity was observed in mouse hippocampus (Jensen et al., 2018) while a low level of GLP-1R-immunoreactivity was revealed in rat hippocampus (Farkas et al., 2021), which may suggest some species difference of the GLP-1R expression in the hippocampus