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TDN, in particular, may represent a complementary anti-obesity or anti-diabetes agent with the benefits of weight and glucose control, but without the gastrointestinal side effects that often limit GLP-1 therapies
Patients initiating GLP-1 therapy for diabetes or weight management who also experience joint pain should maintain a comprehensive approach to musculoskeletal health

However, the authors note that the certainty of evidence was low

Doctors will review medical history, including any past problems with the pancreas, thyroid, or stomach
