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The decision to combine these medications should always involve your prescribing physician and, ideally, an endocrinologist or diabetes educator

GLP-1 receptor agonists should be avoided in patients with a history of medullary thyroid cancer or MEN2

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Bone density considerations also come into play, as bone health during GLP-1 treatment requires adequate calcium and vitamin D intake
Limitations: The absence of a placebo control and the short duration limit generalizability and long-term assessment
