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Nevertheless, GLP-1 RAs have gastrointestinal adverse effects such as abdominal pain, constipation, diarrhea, nausea, and vomiting [7]

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the imidazolium ionic liquid comprises 1- (2-hydroxyethyl) imidazolium tetrafluoroborate ionic liquid, 1- (2-hydroxyethyl) imidazolium hexafluorophosphate ionic liquid, 1- (2-hydroxyethyl) imidazolium trifluoromethanesulfonate ionic liquid and 1- (3-hydroxypropyl) -1H-imidazolium hexafluorophosphate ionic liquid, one of 1- (3-hydroxypropyl) -1H-imidazole tetrafluoroborate ionic liquid, 1- (3-hydroxypropyl) -1H-imidazole trifluoromethanesulfonic acid ionic liquid, 1- (2-hydroxyethyl) imidazole bis-trifluoromethylsulfonyl imide liquid and 1- (3-hydroxypropyl) -1H-imidazole bis-trifluoromethylsulfonyl imide ionic liquid