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These effects depend on the reduction of 5 adenosine monophosphate-activated protein kinase (AMPK) activity in the VMN [29]
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A high prevalence of insulin resistance was identified in a sample of 154 non-diabetic PD patients, with 58% being insulin-resistant as indicated by abnormal Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) scores [157]
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However, it is important to discuss any new or persistent side effects with your healthcare professional so they can assess whether further review or changes to your treatment are needed
