2024 asa guidance glp-1 receptor agonists perioperative aGLP-1 & anesthesia: ( practical approach you can actually use) receptor agonists (e.g., semaglutide, liraglutide, dulaglutide, tirzepatide) are now routine in patients presenting for procedures. For Ozempic: Preoperative Management of Patients

Recent advancementsincluding the approval of oral semaglutide (Rybelsus)have demonstrated the potential for effective oral peptide delivery, though such formulations still face significant pharmacokinetic and formulation-related challenges

They also offer the

Engineering new ligands that specifically target multiple G protein-coupled receptors with desired activity profiles requires time-consuming and expensive cycles of design-make-test-analyse work

These drugs have potent glucose-lowering actions and, additionally, lower body weight through satiety induction while reducing blood pressure and dyslipidemia

This blog covers the impact of high-fiber foods, protein-rich meals, probiotics, allulose, and intermittent fasting on GLP-1