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These symptoms can reduce fluid intake or increase fluid loss, concentrating urine and altering its colour

This convenience factor is a massive reason why these newer-generation medications have become the standard of care
Avoid alcohol for at least 3 hours after injection, and ideally wait 24 hours
The alanine at position 8, the residue immediately adjacent to the DPP-4 cleavage bond, is replaced by alpha-aminoisobutyric acid (Aib), a non-canonical, doubly methylated amino acid whose steric bulk blocks protease access [1]
