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This is because the FDA has noted that the current data isnt enough to fully understand the potential risks
Nonetheless, mice deficient for GRP have impaired glucose tolerance, reduced first-phase insulin secretion and impaired GLP-1 secretion in response to an oral glucose challenge [343]

Contributor Information Michael Colwill, Department of Gastroenterology, St Georges University Hospital NHS Foundation Trust, London, United Kingdom
doi: 10.1016/j.coph.2016.08.005

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