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Description
It is a 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life
Transformation of caspase-1 precursor into the active enzyme promotes IL-1 maturation and secretion by macrophages, thus controlling pathogen infections (Pepe et al., 2021)
The take-home message is that when we treat weight with tirzepatide, its a long-term treatment, not something that happens in 36 months. 2
GLP-1 receptor activation slows gastric emptying and alters gut signaling
Recently, the first approval for a dual-receptor agonist marks an important step in this development
