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As a result, those with endocrine system conditions are not advised to take Ozempic or Wegovy

About 7% of participants taking Wegovy dropped out due to adverse events (versus 3% with placebo)

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GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

However, these medications did not demonstrate statistically significant changes in suicide attempt risks, though the adjusted HR for semaglutide indicated promise
