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Palombit A, Silvestri E, Volpi T, Aiello M, Cecchin D, Bertoldo A, et al

When the body metabolises fat for energy in the absence of sufficient carbohydrate intake, ketone bodies are produced and excreted in urine

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Since estrogen helps keep blood vessels flexible, arteries can stiffen when levels drop, resulting in a rise in blood pressure that forces the heart to work harder

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society, 56, 841851