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At 68 weeks, treatment was stopped but a small group continued taking semaglutide for a year as part of an extension trial

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A safe prescribing decision also considers: eligibility and NHS pathway availability comorbidities and concurrent medicines tolerability and dose escalation patient preference and expectations capacity for follow-up and monitoring The difference between semaglutide and tirzepatide should therefore be framed as a clinical comparison, not a direct consumer recommendation