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A variety of evidence indicates that peripheral injection of GLP-1 analogues may act directly on the hypothalamus and hindbrain or the signal is transmitted to the hindbrain by vagal afferents (57)

It's a relatively uncommon side effect, affecting around 0.4% of people on semaglutide (around 4,000 out of every million people), so most studies only see a small handful of instances to examine

Anti-inflammatory effects of GLP-1R activation in the retina

The guideline view is conservative

How to Prevent Bruising After GLP-1 Injections Bruising from GLP-1 injections, like Ozempic, is uncommon but can happen when tiny blood vessels under the skin are damaged