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Why Weekly Dosing Is Effective Because retatrutide lasts nearly a week, most protocols use: One injection per week Consistent blood levels Reduced hormone fluctuations Lower side effect risk This is why daily dosing is unnecessary

It's an important distinction - and Refills is upfront about it
Reduced food intake means less water from food (which normally contributes 20% of daily fluid intake)

Eating hearty portions of protein also provides a signal boost to muscle protein synthesis
