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The recently initiated large-sized FLOW trial investigating the effects of semaglutide on hard renal outcomes in patients with DKD will provide clarity whether GLP-1 receptor agonists may reduce the burden of DKD in addition to their other beneficial metabolic and cardiovascular effects.
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Meanwhile, Eli Lilly is advancing orforglipron, the first small-molecule GLP-1 receptor agonist for obesity
As states cut Medicaid coverage for GLP-1 drugs, access to obesity treatment is increasingly tied to incomeraising questions for both Medicaid and Medicare.
